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Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice

This study demonstrates that endogenously produced interferon γ (IFN-γ) forms the basis of a tumor surveillance system that controls development of both chemically induced and spontaneously arising tumors in mice. Compared with wild-type mice, mice lacking sensitivity to either IFN-γ (i.e., IFN-γ re...

Ausführliche Beschreibung

Gespeichert in:
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Kaplan, Daniel H., Shankaran, Vijay, Dighe, Anand S., Stockert, Elisabeth, Aguet, Michel, Old, Lloyd J., Schreiber, Robert D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1998
Schlagworte:
Biological Sciences
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22681/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636188/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7556
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