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Insights into drug metabolism by cytochromes P450 from modelling studies of CYP2D6-drug interactions
The cytochromes P450 (CYPs) comprise a vast superfamily of enzymes found in virtually all life forms. In mammals, xenobiotic metabolizing CYPs provide crucial protection from the effects of exposure to a wide variety of chemicals, including environmental toxins and therapeutic drugs. Ideally, the in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268062/ https://ncbi.nlm.nih.gov/pubmed/18026129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707570 |
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