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Agonist-selective mechanisms of GPCR desensitization
The widely accepted model of G protein-coupled receptor (GPCR) regulation describes a system where the agonist-activated receptors couple to G proteins to induce a cellular response, and are subsequently phosphorylated by a family of kinases called the G protein-coupled receptor kinases (GRKs). The...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268061/ https://ncbi.nlm.nih.gov/pubmed/18059321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707604 |
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