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Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice

Hypothalamic-pituitary-adrenocortical (HPA) axis hyperactivity is associated with major depressive disorders, and treatment with classical antidepressants ameliorates not only psychopathological symptoms, but also the dysregulation of the HPA axis. Here, we further elucidated the role of impaired ca...

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Main Authors: Steiner, Michel A, Marsicano, Giovanni, Nestler, Eric J, Holsboer, Florian, Lutz, Beat, Wotjak, Carsten T
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267923/
https://ncbi.nlm.nih.gov/pubmed/17976922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2007.09.008
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