Chimeric coronavirus-like particles carrying severe acute respiratory syndrome coronavirus (SCoV) S protein protect mice against challenge with SCoV

We tested the efficacy of coronavirus-like particles (VLPs) for protecting mice against severe acute respiratory syndrome coronavirus (SCoV) infection. Coexpression of SCoV S protein and E, M and N proteins of mouse hepatitis virus in 293T or CHO cells resulted in the efficient production of chimeri...

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Detalhes bibliográficos
Main Authors: Lokugamage, Kumari G., Yoshikawa-Iwata, Naoko, Ito, Naoto, Watts, Douglas M., Wyde, Philip R., Wang, Nan, Newman, Patrick, Kent Tseng, Chien-Te, Peters, C.J., Makino, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267761/
https://ncbi.nlm.nih.gov/pubmed/18191004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.11.092
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