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Predicting synthetic rescues in metabolic networks

An important goal of medical research is to develop methods to recover the loss of cellular function due to mutations and other defects. Many approaches based on gene therapy aim to repair the defective gene or to insert genes with compensatory function. Here, we propose an alternative, network-base...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Motter, Adilson E, Gulbahce, Natali, Almaas, Eivind, Barabási, Albert-László
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267730/
https://ncbi.nlm.nih.gov/pubmed/18277384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.1
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