Association between the PPP3CC gene, coding for the calcineurin gamma catalytic subunit, and bipolar disorder

BACKGROUND: Calcineurin is a neuron-enriched phosphatase that regulates synaptic plasticity and neuronal adaptation. Activation of calcineurin, overall, antagonizes the effects of the cyclic AMP activated protein/kinase A. Thus, kinase/phosphatase dynamic balance seems to be critical for transition...

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Detalhes bibliográficos
Main Authors: Mathieu, Flavie, Miot, Stéphanie, Etain, Bruno, El Khoury, Marie-Anne, Chevalier, Fabien, Bellivier, Frank, Leboyer, Marion, Giros, Bruno, Tzavara, Eleni T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Short Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267477/
https://ncbi.nlm.nih.gov/pubmed/18201382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-9081-4-2
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