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Sargassum fusiforme fraction is a potent and specific inhibitor of HIV-1 fusion and reverse transcriptase

Sargassum fusiforme (Harvey) Setchell has been shown to be a highly effective inhibitor of HIV-1 infection. To identify its mechanism of action, we performed bioactivity-guided fractionation on Sargassum fusiforme mixture. Here, we report isolation of a bioactive fraction SP4-2 (S. fusiforme), which...

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Bibliographische Detailangaben
Hauptverfasser: Paskaleva, Elena E, Lin, Xudong, Duus, Karen, McSharry, James J, Veille, Jean-Claude L, Thornber, Carol, Liu, Yanze, Lee, David Yu-Wei, Canki, Mario
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267448/
https://ncbi.nlm.nih.gov/pubmed/18197976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-8
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