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The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing

The ubiquitin-like SUMO system functions by a cyclic process of modification and demodification, and recent data suggest that the nucleolus is a site of sumoylation–desumoylation cycles. For example, the tumour suppressor ARF stimulates sumoylation of nucleolar proteins. Here, we show that the nucle...

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Hlavní autoři: Haindl, Markus, Harasim, Thomas, Eick, Dirk, Muller, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267381/
https://ncbi.nlm.nih.gov/pubmed/18259216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.3
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