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The epigenetic signature of CFTR expression is co-ordinated via chromatin acetylation through a complex intronic element
The CFTR (cystic fibrosis transmembrane conductance regulator) gene is a tightly regulated and differentially expressed transcript in many mucosal epithelial cell types. It appears that DNA sequence variations alone do not explain CFTR-related gastrointestinal disease patterns and that epigenetic mo...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2267364/ https://ncbi.nlm.nih.gov/pubmed/17848139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070282 |
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