Regulation of apoptosis signal-regulating kinase 1 by protein phosphatase 2Cϵ

ASK1 (apoptosis signal-regulating kinase 1), a MKKK (mitogen-activated protein kinase kinase kinase), is activated in response to cytotoxic stresses, such as H(2)O(2) and TNFα (tumour necrosis factor α). ASK1 induction initiates a signalling cascade leading to apoptosis. After exposure of cells to H...

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Autors principals: Saito, Jun-ichi, Toriumi, Shinnosuke, Awano, Kenjiro, Ichijo, Hidenori, Sasaki, Keiichi, Kobayashi, Takayasu, Tamura, Shinri
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267319/
https://ncbi.nlm.nih.gov/pubmed/17456047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070231
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