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Fibulin-5 binds human smooth-muscle cells through α5β1 and α4β1 integrins, but does not support receptor activation

Fibulin-5, an extracellular matrix glycoprotein expressed in elastin-rich tissues, regulates vascular cell behaviour and elastic fibre deposition. Recombinant full-length human fibulin-5 supported primary human aortic SMC (smooth-muscle cell) attachment through α5β1 and α4β1 integrins. Cells on fibu...

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Detalhes bibliográficos
Main Authors: Lomas, Amanda C., Mellody, Kieran T., Freeman, Lyle J., Bax, Daniel V., Shuttleworth, C. Adrian, Kielty, Cay M.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267297/
https://ncbi.nlm.nih.gov/pubmed/17472576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070400
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