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Meta-Analysis of BRCA1 and BRCA2 Penetrance

PURPOSE: Genetic counseling is now routinely offered to individuals at high risk of carrying a BRCA1 or BRCA2 mutation. Risk prediction provided by the counselor requires reliable estimates of the mutation penetrance. Such penetrance has been investigated by studies worldwide. The reported estimates...

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Detalhes bibliográficos
Main Authors: Chen, Sining, Parmigiani, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267287/
https://ncbi.nlm.nih.gov/pubmed/17416853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2006.09.1066
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