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A Physical Model of Axonal Elongation: Force, Viscosity, and Adhesions Govern the Mode of Outgrowth

Whether the axonal framework is stationary or moves is a central debate in cell biology. To better understand this problem, we developed a mathematical model that incorporates force generation at the growth cone, the viscoelastic properties of the axon, and adhesions between the axon and substrate....

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Detalhes bibliográficos
Main Authors: O'Toole, Matthew, Lamoureux, Phillip, Miller, Kyle E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267140/
https://ncbi.nlm.nih.gov/pubmed/18178646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.117424
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