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Molecular Dynamics Simulations of Hemoglobin A in Different States and Bound to DPG: Effector-Linked Perturbation of Tertiary Conformations and HbA Concerted Dynamics

Recent functional studies reported on human adult hemoglobin (HbA) show that heterotropic effector-linked tertiary structural changes are primarily responsible for modulating the oxygen affinity of hemoglobin. We present the results of 6-ns molecular dynamics simulations performed to gain insights i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Laberge, Monique, Yonetani, Takashi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267116/
https://ncbi.nlm.nih.gov/pubmed/18096633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.114942
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