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There and (Slowly) Back Again: Entropy-Driven Hysteresis in a Model of DNA Overstretching

When pulled along its axis, double-stranded DNA elongates abruptly at a force of ∼65 pN. Two physical pictures have been developed to describe this overstretched state. The first proposes that strong forces induce a phase transition to a molten state consisting of unhybridized single strands. The se...

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Detalhes bibliográficos
Main Authors: Whitelam, Stephen, Pronk, Sander, Geissler, Phillip L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267113/
https://ncbi.nlm.nih.gov/pubmed/17981894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.117036
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