Inhibition of Luteinizing Hormone Secretion by Testosterone in Men Requires Aromatization for Its Pituitary But Not Its Hypothalamic Effects: Evidence from the Tandem Study of Normal and Gonadotropin-Releasing Hormone-Deficient Men

Context: Studies on the regulation of LH secretion by sex steroids in men are conflicting. Objective: Our aims were to determine the relative contributions of testosterone (T) and estradiol (E(2)) to LH regulation and localize their sites of negative feedback. Design: This was a prospective study wi...

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Autori principali: Pitteloud, Nelly, Dwyer, Andrew A., DeCruz, Suzzunne, Lee, Hang, Boepple, Paul A., Crowley, William F., Hayes, Frances J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2008
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266963/
https://ncbi.nlm.nih.gov/pubmed/18073301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2007-2156
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