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Dramatic inhibition of osteoclast sealing ring formation and bone resorption in vitro by a WASP-peptide containing pTyr294 amino acid

Wiskott Aldrich Syndrome protein (WASP) has a unique regulatory role in sealing ring formation and bone resorption in osteoclasts. Here, using the TAT-transduction method, we show the possible role of WASP domain(s) in sealing ring formation and bone resorption. Transduction of TAT-fused full-length...

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Detalhes bibliográficos
Main Authors: Ma, Tao, Samanna, Venkatesababa, Chellaiah, Meenakshi A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266921/
https://ncbi.nlm.nih.gov/pubmed/18289379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-3-4
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