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Drug transporters: recent advances concerning BCRP and tyrosine kinase inhibitors

Multidrug resistance is often associated with the (over)expression of drug efflux transporters of the ATP-binding cassette (ABC) protein family. This minireview discusses the role of one selected ABC-transporter family member, the breast cancer resistance protein (BCRP/ABCG2), in the (pre)clinical e...

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Detalhes bibliográficos
Main Authors: Lemos, C, Jansen, G, Peters, G J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266858/
https://ncbi.nlm.nih.gov/pubmed/18253130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604213
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