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Population-Wide Emergence of Antiviral Resistance during Pandemic Influenza

BACKGROUND: The emergence of neuraminidase inhibitor resistance has raised concerns about the prudent use of antiviral drugs in response to the next influenza pandemic. While resistant strains may initially emerge with compromised viral fitness, mutations that largely compensate for this impaired fi...

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Detalhes bibliográficos
Main Authors: Moghadas, Seyed M., Bowman, Christopher S., Röst, Gergely, Wu, Jianhong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266801/
https://ncbi.nlm.nih.gov/pubmed/18350174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001839
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