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Functionally Active T1-T1 Interfaces Revealed by the Accessibility of Intracellular Thiolate Groups in Kv4 Channels

Gating of voltage-dependent K(+) channels involves movements of membrane-spanning regions that control the opening of the pore. Much less is known, however, about the contributions of large intracellular channel domains to the conformational changes that underlie gating. Here, we investigated the fu...

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Detalhes bibliográficos
Main Authors: Wang, Guangyu, Shahidullah, Mohammad, Rocha, Carmen A., Strang, Candace, Pfaffinger, Paul J., Covarrubias, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266617/
https://ncbi.nlm.nih.gov/pubmed/15955876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509288
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