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K Channel Subconductance Levels Result from Heteromeric Pore Conformations
Voltage-gated K channels assemble from four identical subunits symmetrically arranged around a central permeation pathway. Each subunit harbors a voltage-sensing domain. The sigmoidal nature of the activation kinetics suggests that multiple sensors need to undergo a conformational change before the...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266570/ https://ncbi.nlm.nih.gov/pubmed/16043772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509253 |
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