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The MuLV 4070A G541R Env mutation decreases the stability and alters the conformation of the TM ectodomain

Virus-cell and cell-cell fusion events are affected by various properties of the fusogenic Env protein on the cell surface. The G541R mutation within the TM ectodomain of murine leukemia virus (MuLV) 4070A arose by positive selection in viral passage and results in a reduction of cell-cell fusion ev...

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Autors principals: Schneider, William M., Zheng, Haiyan, Coté, Marie L., Roth, Monica J.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266080/
https://ncbi.nlm.nih.gov/pubmed/17961622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.09.033
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