A Mouse Model of Metabolic Syndrome; Increase in Visceral Adipose Tissue Precedes the Development of Fatty Liver and Insulin Resistance in High-Fat Diet-Fed Male KK/Ta Mice

To determine the relative contribution of obesity and visceral white adipose tissue (WAT) to metabolic syndrome, we developed a model that is susceptible to high-fat diet-induced obesity and insulin resistance using male KK/Ta mice. The ratio of WAT weight to body weight was greater in the high-fat...

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Bibliographic Details
Main Authors: Akagiri, Satomi, Naito, Yuji, Ichikawa, Hiroshi, Mizushima, Katsura, Takagi, Tomohisa, Handa, Osamu, Kokura, Satoshi, Yoshikawa, Toshikazu
Format: Artigo
Language:Inglês
Published: the Society for Free Radical Research Japan 2008
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266061/
https://ncbi.nlm.nih.gov/pubmed/18385833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.2008022
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