Human dendritic cells transfected with allergen-DNA stimulate specific immunoglobulin G4 but not specific immunoglobulin E production of autologous B cells from atopic individuals in vitro

Atopic/allergic diseases are characterized by T helper 2 (Th2)-dominated immune responses resulting in immunoglobulin E (IgE) production. DNA-based immunotherapies have been shown to shift the immune response towards Th1 in animal models. In further studies we showed that human dendritic cells (DC)...

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Detalhes bibliográficos
Main Authors: König, Bettina, Petersen, Arnd, Bellinghausen, Iris, Böttcher, Ingo, Becker, Wolf-Meinhard, Knop, Jürgen, Saloga, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266010/
https://ncbi.nlm.nih.gov/pubmed/17848164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02633.x
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