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CTLA-4 regulates allergen response by modulating GATA-3 protein level per cell
T helper type 2 (Th2) cell differentiation requires the expression of GATA-3, a transcription factor that allows transcriptional activation of Th2 cytokine genes through chromatin remodelling. We investigated the role of the negative costimulatory receptor cytotoxic T-lymphocyte antigen 4 (CTLA-4) i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265929/ https://ncbi.nlm.nih.gov/pubmed/17313444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02537.x |
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