Bone morphogenetic protein-2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell development

T-cell differentiation is driven by a complex network of signals mainly derived from the thymic epithelium. In this study we demonstrate in the human thymus that cortical epithelial cells produce bone morphogenetic protein 2 (BMP2) and BMP4 and that both thymocytes and thymic epithelium express all...

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Detalhes bibliográficos
Main Authors: Cejalvo, Teresa, Sacedón, Rosa, Hernández-López, Carmen, Diez, Blanca, Gutierrez-Frías, Cruz, Valencia, Jaris, Zapata, Agustín G, Varas, Alberto, Vicente, Angeles
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265915/
https://ncbi.nlm.nih.gov/pubmed/17425602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02541.x
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