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Statins inhibit lymphocyte homing to peripheral lymph nodes

Lymphocyte homing to peripheral lymph nodes is governed by adhesion molecules, including lymphocyte function-associated antigen 1 (LFA-1). Statins are 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and exert anti-inflammatory effects, e.g. inhibition of LFA-1. It is still not known wheth...

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Detalhes bibliográficos
Main Authors: Schramm, René, Menger, Michael D, Harder, Yves, Schmits, Rudolf, Adam, Oliver, Weitz-Schmidt, Gabriele, Schäfers, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265897/
https://ncbi.nlm.nih.gov/pubmed/17140403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02505.x
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