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Antigen-specific immunoglobulin E(+) B cells are preferentially localized within germinal centres
Allergen-specific immunoglobulin E (IgE) mediates immediate-type hypersensitivity reactions and plays a central role in allergic diseases. Although antigen-driven B-cell maturation and isotype switching occur within germinal centres (GCs), the role of GCs in IgE production is poorly understood. In v...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265882/ https://ncbi.nlm.nih.gov/pubmed/17163956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02509.x |
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