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Fas ligand exerts its pro-inflammatory effects via neutrophil recruitment but not activation

Fas ligand (FasL) expression induces apoptosis of activated T cells and has been suggested as a strategy to inhibit graft rejection. Unfortunately, the use of FasL to confer ‘immune privilege’ in this setting has been hampered by the finding that it may also provoke a destructive granulocytic respon...

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Autors principals: Dupont, Peter J, Warrens, Anthony N
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Inc 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265864/
https://ncbi.nlm.nih.gov/pubmed/17233740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02504.x
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