Tacrolimus treatment of plasmacytoid dendritic cells inhibits dinucleotide (CpG-)-induced tumour necrosis factor-alpha secretion

Tacrolimus is a widely used immunosuppressive agent. Although T cells are the main targets of these pharmacological drugs, antigen presentation may also be affected. Among antigen-presenting cells, plasmacytoid dendritic cells (PDCs) are the main source of type I interferons upon microbial challenge...

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Detalhes bibliográficos
Main Authors: Naranjo-Gómez, Mar, Climent, Nuria, Cos, Joan, Oliva, Harold, Bofill, Margarita, Gatell, José M, Gallart, Teresa, Pujol-Borrell, Ricardo, Borràs, Francesc E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265822/
https://ncbi.nlm.nih.gov/pubmed/16930148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02460.x
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