Exploring the Developmental Overnutrition Hypothesis Using Parental–Offspring Associations and FTO as an Instrumental Variable

BACKGROUND: The developmental overnutrition hypothesis suggests that greater maternal obesity during pregnancy results in increased offspring adiposity in later life. If true, this would result in the obesity epidemic progressing across generations irrespective of environmental or genetic changes. I...

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Main Authors: Lawlor, Debbie A, Timpson, Nicholas J, Harbord, Roger M, Leary, Sam, Ness, Andy, McCarthy, Mark I, Frayling, Timothy M, Hattersley, Andrew T, Smith, George Davey
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265763/
https://ncbi.nlm.nih.gov/pubmed/18336062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0050033
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