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Identification of cellular pathways affected by Sortin2, a synthetic compound that affects protein targeting to the vacuole in Saccharomyces cerevisiae

BACKGROUND: Sortin2 is a low mass compound that interferes with vacuolar delivery of proteins in plants and yeast. The Sortin2 phenotype was tested in Arabidopsis thaliana and found to be reversible upon drug removal, demonstrating the ability of chemical genomics to induce reversible phenotypes tha...

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Main Authors: Norambuena, Lorena, Zouhar, Jan, Hicks, Glenn R, Raikhel, Natasha V
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265672/
https://ncbi.nlm.nih.gov/pubmed/18179719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-8-1
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