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IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis

Nuclear factor κB (NF-κB) is involved in multiple skeletal muscle disorders, but how it functions in differentiation remains elusive given that both anti- and promyogenic activities have been described. In this study, we resolve this by showing that myogenesis is controlled by opposing NF-κB signali...

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Main Authors: Bakkar, Nadine, Wang, Jingxin, Ladner, Katherine J., Wang, Huating, Dahlman, Jason M., Carathers, Micheal, Acharyya, Swarnali, Rudnicki, Michael A., Hollenbach, Andrew D., Guttridge, Denis C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265568/
https://ncbi.nlm.nih.gov/pubmed/18299349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707179
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