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Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis
During meiosis, homologous chromosomes undergo synapsis and recombination. We identify TEX15 as a novel protein that is required for chromosomal synapsis and meiotic recombination. Loss of TEX15 function in mice causes early meiotic arrest in males but not in females. Specifically, TEX15-deficient s...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265566/ https://ncbi.nlm.nih.gov/pubmed/18283110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200709057 |
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