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Mitogenic and oncogenic properties of the small G protein Rap1b

It has been widely reported that the small GTP-binding protein Rap1 has an anti-Ras and anti-mitogenic activity. Thus, it is generally accepted that a normal physiological role of Rap1 proteins is to antagonize Ras mitogenic signals, presumably by forming nonproductive complexes with proteins that a...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Altschuler, Daniel L., Ribeiro-Neto, Fernando
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1998
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22655/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636174/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7475
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