Genome-Wide Assessments Reveal Extremely High Levels of Polymorphism of Two Active Families of Mouse Endogenous Retroviral Elements

Endogenous retroviral elements (ERVs) in mice are significant genomic mutagens, causing ∼10% of all reported spontaneous germ line mutations in laboratory strains. The majority of these mutations are due to insertions of two high copy ERV families, the IAP and ETn/MusD elements. This significant lev...

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Bibliografiske detaljer
Main Authors: Zhang, Ying, Maksakova, Irina A., Gagnier, Liane, van de Lagemaat, Louie N., Mager, Dixie L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265474/
https://ncbi.nlm.nih.gov/pubmed/18454193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000007
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