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MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

MicroRNAs (miRNAs) are small RNAs of 19 to 25 nucleotides that are negative regulators of gene expression. To determine whether miRNAs are associated with cytogenetic abnormalities and clinical features in acute myeloid leukemia (AML), we evaluated the miRNA expression of CD34(+) cells and 122 untre...

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Bibliografiske detaljer
Main Authors: Garzon, Ramiro, Volinia, Stefano, Liu, Chang-Gong, Fernandez-Cymering, Cecilia, Palumbo, Tiziana, Pichiorri, Flavia, Fabbri, Muller, Coombes, Kevin, Alder, Hansjuerg, Nakamura, Tatsuya, Flomenberg, Neal, Marcucci, Guido, Calin, George A., Kornblau, Steven M., Kantarjian, Hagop, Bloomfield, Clara D., Andreeff, Michael, Croce, Carlo M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265455/
https://ncbi.nlm.nih.gov/pubmed/18187662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-098749
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