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RNAi Screen Reveals an Abl Kinase-Dependent Host Cell Pathway Involved in Pseudomonas aeruginosa Internalization

Internalization of the pathogenic bacterium Pseudomonas aeruginosa by non-phagocytic cells is promoted by rearrangements of the actin cytoskeleton, but the host pathways usurped by this bacterium are not clearly understood. We used RNAi-mediated gene inactivation of ∼80 genes known to regulate the a...

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Detalles Bibliográficos
Autores principales: Pielage, Julia F., Powell, Kimberly R., Kalman, Daniel, Engel, Joanne N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265438/
https://ncbi.nlm.nih.gov/pubmed/18369477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000031
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