Activation of Invariant NKT Cells Exacerbates Experimental Visceral Leishmaniasis

We report that natural killer T (NKT) cells play only a minor physiological role in protection from Leishmania donovani infection in C57BL/6 mice. Furthermore, attempts at therapeutic activation of invariant NKT (iNKT) cells with α-galactosylceramide (α-GalCer) during L. donovani infection exacerbat...

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Hlavní autoři: Stanley, Amanda C., Zhou, Yonghong, Amante, Fiona H., Randall, Louise M., Haque, Ashraful, Pellicci, Daniel G., Hill, Geoff R., Smyth, Mark J., Godfrey, Dale I., Engwerda, Christian R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265425/
https://ncbi.nlm.nih.gov/pubmed/18463695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000028
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