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Inhibition of “self” engulfment through deactivation of myosin-II at the phagocytic synapse between human cells

Phagocytosis of foreign cells or particles by macrophages is a rapid process that is inefficient when faced with “self” cells that display CD47—although signaling mechanisms in self-recognition have remained largely unknown. With human macrophages, we show the phagocytic synapse at cell contacts inv...

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Autores principales: Tsai, Richard K., Discher, Dennis E.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265407/
https://ncbi.nlm.nih.gov/pubmed/18332220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708043
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