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The Caenorhabditis elegans nephrocystins act as global modifiers of cilium structure

Nephronophthisis (NPHP) is the most common genetic cause of end-stage renal disease in children and young adults. In Chlamydomonas reinhardtii, Caenorhabditis elegans, and mammals, the NPHP1 and NPHP4 gene products nephrocystin-1 and nephrocystin-4 localize to basal bodies or ciliary transition zone...

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Autores principales: Jauregui, Andrew R., Nguyen, Ken C.Q., Hall, David H., Barr, Maureen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265406/
https://ncbi.nlm.nih.gov/pubmed/18316409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707090
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