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Membrane depolarization inhibits spiral ganglion neurite growth via activation of multiple types of voltage sensitive calcium channels and calpain

The effect of membrane electrical activity on spiral ganglion neuron (SGN) neurite growth remains unknown despite its relevance to cochlear implant technology. We demonstrate that membrane depolarization delays the initial formation and inhibits the subsequent extension of cultured SGN neurites. Thi...

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Autors principals: Roehm, Pamela C., Xu, Ningyong, Woodson, Erika A., Green, Steven H., Hansen, Marlan R.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265381/
https://ncbi.nlm.nih.gov/pubmed/18055215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2007.10.014
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