Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells

We developed a method for the efficient generation of functional dopaminergic (DA) neurons from human embryonic stem cells (hESCs) on a large scale. The most unique feature of this method is the generation of homogeneous spherical neural masses (SNMs) from the hESC-derived neural precursors. These S...

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Autori principali: Cho, Myung Soo, Lee, Young-Eun, Kim, Ji Young, Chung, Seungsoo, Cho, Yoon Hee, Kim, Dae-Sung, Kang, Sang-Moon, Lee, Haksup, Kim, Myung-Hwa, Kim, Jeong-Hoon, Leem, Joong Woo, Oh, Sun Kyung, Choi, Young Min, Hwang, Dong-Youn, Chang, Jin Woo, Kim, Dong-Wook
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265201/
https://ncbi.nlm.nih.gov/pubmed/18305158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712359105
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