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Two-step site selection for serine-integrase-mediated excision: DNA-directed integrase conformation and central dinucleotide proofreading

Bacteriophage-encoded serine-integrases are members of the large family of serine-recombinases and catalyze site-specific integrative recombination between a phage attP site and a bacterial attB site to form an integrated prophage. Prophage excision involves a second site-specific recombination even...

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Detalhes bibliográficos
Main Authors: Ghosh, Pallavi, Bibb, Lori A., Hatfull, Graham F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265153/
https://ncbi.nlm.nih.gov/pubmed/18299577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711649105
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