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Genetic interaction between members of the Vangl family causes neural tube defects in mice
Neural tube defects (NTDs) are very frequent congenital abnormalities in humans. Recently, we have documented independent association of Vangl1 and Vangl2 gene mutations with NTDs. In the Looptail mouse, homozygosity (but not heterozygosity) for loss-of-function alleles at Vangl2 causes the severe N...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265143/ https://ncbi.nlm.nih.gov/pubmed/18296642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712126105 |
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