TP53 Mutations and Survival in Squamous-Cell Carcinoma of the Head and Neck

BACKGROUND: The abrogation of function of the tumor-suppressor protein p53 as a result of mutation of its gene, TP53, is one of the most common genetic alterations in cancer cells. We evaluated TP53 mutations and survival in patients with squamous-cell carcinoma of the head and neck. METHODS: A tota...

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Auteurs principaux: Poeta, M. Luana, Manola, Judith, Goldwasser, Meredith A., Forastiere, Arlene, Benoit, Nicole, Califano, Joseph A., Ridge, John A., Goodwin, Jarrard, Kenady, Daniel, Saunders, John, Westra, William, Sidransky, David, Koch, Wayne M.
Format: Artigo
Langue:Inglês
Publié: 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2263014/
https://ncbi.nlm.nih.gov/pubmed/18094376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa073770
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