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GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

How breast cancers are able to disseminate and metastasize is poorly understood. Using hyperplasia transplant system, we show that tumor dissemination and metastasis occur in discrete steps during tumor progression. Bioinformatic analysis revealed that loss of the transcription factor GATA-3 marked...

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Detalhes bibliográficos
Main Authors: Kouros-Mehr, Hosein, Bechis, Seth K., Slorach, Euan M., Littlepage, Laurie E., Egeblad, Mikala, Ewald, Andrew J., Pai, Sung-Yun, Ho, I-Cheng, Werb, Zena
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262951/
https://ncbi.nlm.nih.gov/pubmed/18242514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.01.011
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