GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

How breast cancers are able to disseminate and metastasize is poorly understood. Using hyperplasia transplant system, we show that tumor dissemination and metastasis occur in discrete steps during tumor progression. Bioinformatic analysis revealed that loss of the transcription factor GATA-3 marked...

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Main Authors: Kouros-Mehr, Hosein, Bechis, Seth K., Slorach, Euan M., Littlepage, Laurie E., Egeblad, Mikala, Ewald, Andrew J., Pai, Sung-Yun, Ho, I-Cheng, Werb, Zena
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262951/
https://ncbi.nlm.nih.gov/pubmed/18242514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.01.011
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