Nucleotide Sequence Variation within the PI3K p85 Alpha Gene Associates with Alcohol Risk Drinking Behaviour in Adolescents

BACKGROUND: While the phosphatidylinositol 3-kinase (PI3K)-dependent signaling pathway is typically known to regulate cell growth and survival, emerging evidence suggest a role for this pathway in regulating the behavioural responses to addictive drugs. METHODOLOGY/PRINCIPAL FINDINGS: To investigate...

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Main Authors: Desrivières, Sylvane, Krause, Kristina, Dyer, Anne, Frank, Josef, Blomeyer, Dorothea, Lathrop, Mark, Mann, Karl, Banaschewski, Tobias, Laucht, Manfred, Schumann, Gunter
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262154/
https://ncbi.nlm.nih.gov/pubmed/18335044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001769
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