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Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

The cell cycle inhibitor p21/WAF1/Cip1 is expressed in many cell types and is regulated by p53-dependent and p53-independent mechanisms. p21 is an important regulator of hepatocyte cell cycle, differentiation, and liver development, but little is known about the regulation of its synthesis in hepato...

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Библиографические подробности
Главные авторы: Moustakas, Aristidis, Kardassis, Dimitris
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1998
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC22615/
https://ncbi.nlm.nih.gov/pubmed/9618481
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